Top-tier Medical Device Manufacturer Renews Agreement for another 5 years with OmniComm

Fort Lauderdale, FL, March 9, 2010 - OmniComm Systems, Inc. (OTC: OMCM.OB), a global provider of eClinical solutions, announced today that a leading cardiovascular medical device manufacturer has renewed its contract with the company for another 5 years. The agreement extends and expands the previous five-year agreement which generated over $2.5 Million in revenue for the company over the past three years. The company expects revenue for this customer to increase.

"We are grateful for the opportunity to continue an important long-standing relationship," said Stephen Johnson, COO of OmniComm Systems. "We have been able to demonstrate to this client, through a collaborative approach, the benefits over time of operational efficiencies gained through use of our products and services. As a result, we expect the customer to expand its relationship with OmniComm." The manufacturer, who focuses on providing innovative therapeutic solutions for complex medical problems, is currently running numerous studies involving several different product lines, and plans to deploy these studies using OmniComm’s Software as a Service (SaaS) offering.

About OmniComm
OmniComm Systems, Inc. (www.OmniComm.com) provides customer-driven Internet solutions to pharmaceutical, biotechnology, research and medical device organizations that conduct life changing clinical trial research. OmniComm's growing base of satisfied customers is a direct result of the company's commitment to deliver products and services that ensure ease of use, faster study build, ease of integration and better performance. OmniComm's client intuitive pricing model allows companies that range from small, to mid-size to large-scale institutions to efficiently capitalize on their clinical research investments. OmniComm Systems, Inc has U.S. headquarters in Fort Lauderdale, FL and European headquarters in Bonn, Germany, with satellite offices in New Jersey and the United Kingdom, as well as sales offices throughout the U.S. and Europe.

Safe Harbor Disclaimer
Safe Harbor Disclaimer Statements made by OmniComm included in this release may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements involve a number of risks and uncertainties such as the Company's ability to obtain new contracts and accurately estimate net revenues due to uncertain regulatory guidance, variability in size, scope and duration of projects, and internal issues at the sponsoring client, integration of acquisitions, competitive factors, technological development, and market demand. As a result, actual results may differ materially from any financial outlooks stated herein. Further information on potential factors that could affect the Company's financial results can be found in the Company's Reports on Form 10-K and 10-Q filed with the Securities and Exchange Commission. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise.

CONTACT: Stephen Johnson at: + 1 954-377-1726

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